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Bio lab report

This cell contained all the information to create an adult made of trillions of cells. We know that the egg does not provide centrioles, so the origin of all the centrioles in our body is from the sperm bio lab report the father. However the sperm have only one centriole, so where does the second centriole come from?

Ciliogenesis: During my postdoctoral research in the lab of Charles Zuker in the University of California, I studied the mechanism of cilia formation. To identify the genes required for cilia formation, I have developed a novel bioinformatic screen and found a large collection of genes required for cilia formation. Cep152 is a key regulator in the initiation of centriole duplication. Before our publication, for nearly ten years, it was believed that Asterless was only essential for the function of the mature centrosome. The major goal of this project is to study develop a rabbit expressing POC1-Neon to study the role of sperm centrioles. The major goal of this project is to study the mechanism of pericentriolar material assembly during centrosome biogenesis in Drosophila melanogaster. The major goal of this project is to identify the commercial need for male factor infertility test.

Fishman EL, Jo K, Nguyen QPH, Kong D, Royfman R, Cekic AR, Khanal S, Miller A, Simerly C, Schatten G, Loncarek J, Mennella V, and Avidor-Reiss T. A Novel Atypical Sperm Centriole is Functional During Human Fertilization. Fishman EL, Jo K, Ha A, Royfman R, Zinn A, Krishnamurthy M, Avidor-Reiss T. Atypical centrioles are present in Tribolium sperm. Avidor-Reiss T, Ha A, Basiri ML.

Transition Zone Migration: A Mechanism for Cytoplasmic Ciliogenesis and Postaxonemal Centriole Elongation. Centriole Remodeling During Spermiogenesis in Drosophila. Khire A, Vizuet AA, Davila E, Avidor-Reiss T. Asterless Reduction during Spermiogenesis Is Regulated by Plk4 and Is Essential for Zygote Development in Drosophila. Shared and Distinct Mechanisms of Compartmentalized and Cytosolic Ciliogenesis. Avidor-Reiss T, Khire A, Fishman EL, Jo KH.

Basiri ML, Ha A, Chadha A, Clark NM, Polyanovsky A, Cook B, Avidor-Reiss T. A migrating ciliary gate compartmentalizes the site of axoneme assembly in Drosophila spermatids. From the cytoplasm into the cilium: Bon voyage. Blachon S, Khire A, and Avidor-Reiss T.

The Origin of the Second Centriole of the Zygote. Cell Cycle Regulation of the Centrosome and Cilium. Gopalakrishnan, J, Chim, YCF, Ha, A, Basiri, ML, Lerit DA, Rusan NM, and Avidor-Reiss, T. Tubulin nucleotide status controls Sas-4-dependent pericentriolar material recruitment.

Centriole duplication and inheritance in Drosophila melanogaster. The Centrosome: Cell and Molecular Mechanisms of Functions and Dysfunctions in Disease” ed. Chapter 1: Centriole duplication and inheritance in Drosophila melanogaster. Gopalakrishnan J, Mennella V, Blachon S, Zhai B, Smith AH, Megraw TL, Nicastro D, Gygi SP, Agard DA, and Avidor-Reiss, T.

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